The world's first-in-class miRNA therapeutics to cure diabetes by pancreatic beta cell regeneration
PR89334
SEOUL, South Korea, May 7, 2021 /PRNewswire=KYODO JBN/ --
RNA therapeutics, a breakthrough for major modern diseases such as Corona 19,
orphan diseases, and chronic diseases
Nexturn Bio Inc. completed its first investment review on RosVivo Therapeutics
Inc., a new miRNA drug company in the U.S.
Nexturn Bio Inc., a subsidiary of Nexturn Bioscience Co., Ltd. (KOSDAQ:89140),
has selected its first technological investment target to expand its new bio
business. Nexturn Bio announced that it has secured a 50% stake in RosVivo
Therapeutics, Inc. as its final investment destination under support from its
parent company Nexturn Bioscience Co., Ltd. RosVivo, planned to receive
investment from Nexturn Bio Inc., is an R&D company for miRNA (MicroRNA) new
drugs in Nevada.
While the development of RNA vaccines has been spotlighted since the Corona-19
outbreak, RSVI-301, a new drug pipeline of RosVivo targeting diabetes, also
uses miRNA (micro RNA). Consisting of 20–24 nucleotide, miRNA is known as a
"small cleaner" in the body that naturally regulates metabolic processes of
genes and proteins. Since these miRNA treatments inject human-derived genetic
materials, they are expected to be of greater value in stability than
conventional mRNA treatments using external genetic materials like viruses.
In particular, miR-10-5p study, underlying study of the new drug development,
enables the researchers to observe the world's first pancreatic beta cell
regeneration. Nexturn Bio Inc. and RosVivo Therapeutics, Inc. said they will
appoint Scientific Advisory Board (SAB) for thorough verification as it is
important precedent for diabetes research. The advisors will be staffed at
several major national Hospitals, such as Stanford University of Medicine, to
support professional advice throughout the drug development.
Beta cells have been regenerated as much as normal mice (first) after
miR-10a-5p injection in diabetic mice (third), induced by high-fat carbohydrate
diet.
Nexturn Bio Inc. plans to catch both "innovation" and "marketability" through
RosVivo's new miRNA drug. It has been reported that CEO Song Myung-Seok
participated to discover candidates while establishing a subsidiary. "RosVivo
is the first official investment of Nexturn Bio, and RSVI-301 of RosVivo will
be an innovative opportunity to open a new era of medicine after mRNA and
challenge the complete cure of diabetes," said the CEO.
SOURCE NEXTURN Bio Inc.
Image Attachments Links:
Link: http://asianetnews.net/view-attachment?attach-id=390559
Caption: miR-10-5p performs as a key factor in GI dysmotility and Diabetes via the
KLF11-KIT pathway
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