PR91463

HOLLAND, Mich., Sept. 7, 2021 /PRNewswire=KYODO JBN/ --

-- The highly-anticipated Open Source Imaging Consortium (OSIC) database is

driven by global experts in pulmonology, radiology and artificial intelligence,

and is the most diverse and largest for rare fibrotic lung diseases

The Open Source Imaging Consortium (OSIC) (https://www.osicild.org/ ) today

announced the launch of its global, data-rich repository of anonymized HRCT

scans and clinical information regarding interstitial lung diseases (ILDs).

This first-of-its-kind database is the world's largest and most diverse, with a

plethora of real world clinical and imaging data that is both multi-ethnic and

multi-center. The OSIC Data Repository

(https://www.osicild.org/data-repository.html )currently houses close to 1,500

anonymized and quality-controlled scans with accompanying data, and has an

additional 5,000 in the quality control queue. It is on track to reach its goal

of 15,000 anonymized scans, available to OSIC members, by first quarter 2022.

OSIC – a global, 501(c)(3), not-for-profit cooperative effort between academia,

industry and patient advocacy groups – was created to enable rapid, open source

advances in the fight against idiopathic pulmonary fibrosis (IPF), fibrosing

ILDs, and other respiratory diseases, including emphysematous conditions.

Radiologists, clinicians, computational scientists, and industry competitors

from around the world collaborated for almost three years on the development of

the database itself, and are working together to advance digital imaging

biomarkers for accurate imaging-based diagnosis, prognosis and prediction of

response to therapy. Any OSIC-created algorithms will be made open source for

the benefit of patients everywhere.

"Building the OSIC repository has been a collaboration in its truest sense,

with people from different disciplines, organizations, and countries all coming

together on behalf of patients everywhere. This ability to collect and organize

anonymized imaging and clinical data from across the world is the future of

clinical science," said Dr. Kevin Brown, National Jewish Health & OSIC

pulmonology lead. "We've seen efforts like this in common diseases, but nothing

truly like it for rare diseases. As the OSIC database grows and we continuously

learn from it, a real and substantial improvement in our ability to diagnose

early, to predict outcomes, and to measure responses to therapy will be the

result."

"In recent years, we have seen rapid developments in advanced medical imaging

analysis, but a major obstacle to harnessing this technology used to study

pulmonary fibrosis is the lack of large diverse imaging repositories needed for

computer training," said Dr. Simon Walsh, National Heart and Lung Institute,

Imperial College London & OSIC radiology lead. "OSIC addresses this unmet need

by providing researchers with the data needed to develop AI-based applications

for improving patient care and facilitating precision medicine. Being able to

reliably predict how pulmonary fibrosis will progress in an individual patient

would allow doctors to initiate appropriate treatment at the earliest

opportunity and slow disease progression. It remains one of the most urgent

challenges for effective management for patients with fibrotic lung disease."

The OSIC Data Repository (https://www.osicild.org/data-repository.html )was

built with images and clinical data from a variety of sources, and every scan

has been anonymized with a personal and automated quality control check. The

organization is seeking additional scans from governmental agencies, patient

advocacy groups, and through direct patient outreach. The database has been

vetted by two global GDPR/HIPAA privacy firms, has Central IRB and multiple

institution IRB approvals, and will be managed in compliance with all

applicable privacy laws, regulations, consents and related restrictions.

"The future of medical research depends heavily on our ability to collate

significant amounts of data, and make that data available for detailed and open

scientific investigation. It's a proud moment that OSIC is at the forefront of

this movement," said Dr. David Barber, University College London & OSIC

computational science lead. "Data is the essence of scientific progress and the

OSIC Data Repository (https://www.osicild.org/data-repository.html )already

contains preliminary data rich enough to better understand the causes of

disease, leading to better treatment and patient outcomes."

OSIC is steered by subject-matter experts Dr. Kevin Brown, Dr. Simon Walsh, and

Dr. David Barber. It is also supported by an impressive list of global member

institutions and partners, including the American Lung Association

(https://www.lung.org/ ), EU-IPFF (https://www.eu-ipff.org/ ), PF Warriors

(https://pfwarriors.com/ ), Action for Pulmonary Fibrosis

(https://www.actionpf.org/ ), Boehringer Ingelheim

(https://www.boehringer-ingelheim.com/ ), Siemens Healthineers

(https://www.siemens-healthineers.com/ ), CSL Behring

(https://www.cslbehring.com/ ), Galapagos (https://www.glpg.com/ ), FLUIDDA

(https://www.fluidda.com/ ), Brainomix (https://www.brainomix.com/ ), National

Jewish Health (https://www.nationaljewish.org/home ), National and Kapodistrian

University of Athens (https://en.uoa.gr/ ), Universite de Lyon

(https://www.universite-lyon.fr/ ), Hospices Civils de Lyon

(https://www.chu-lyon.fr/ ), University of Vienna

(https://www.meduniwien.ac.at/web/ ), National Hospital Organization Kinki-Chuo

Chest Medical Center (https://kcmc.hosp.go.jp/ ), Royal Brompton and Harefield

Foundation Trust (https://www.rbht.nhs.uk/ ), University of Arizona College of

Medicine – Phoenix (https://phoenixmed.arizona.edu/about ), Pavilhao Pereira

Filho – Santa Casa de Misericordia de Porto Alegre

(https://www.santacasa.org.br/categoria/pavilhao-pereira-filho ), The Research

Institute of St. Joe's Hamilton (https://research.stjoes.ca/ ), Thirona

(https://thirona.eu/ ), Universita di Genova (https://unige.it/en/ ),

Fondazione Policlinico Universitario Agostino Gemelli

(https://www.policlinicogemelli.it/ ), VIDA Diagnostics (https://vidalung.ai/

), and imvaria (https://www.imvaria.com/ ).

To stay up-to-date on the latest OSIC news, visit https://www.osicild.org/  or

follow the organization on Twitter at @OSICild (https://www.osicild.org/ ).

SOURCE  Open Source Imaging Consortium (OSIC)

CONTACT: Theresa Hennessey Barcy, theresa@tmhpublicrelations.com, 773-960-7276